Recent progress in the chemistry and applications of indolocarbazoles

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications · 1986 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +10

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

Hiroshi Kase, Kazuyuki Iwahashi, Satoshi Nakanishi et al. · Biochemical and Biophysical Research Communications · 1987 · 942 citations

Life Sciences, Medicinal Chemistry, Pharmacology +13

Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

L.F. Bjeldanes, Jeong Yoon Kim, Karl R. Grose et al. · Proceedings of the National Academy of Sciences · 1991 · 593 citations

Medicine, Biochemistry, Pharmacology +17

Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.

Christine Bonnesen, Ian M. Eggleston, John D. Hayes · PubMed · 2001 · 463 citations

Medicine, Oncology, Pharmacology +17

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation

Ellen Fritsche, Claudia Schäfer, Christian Calles et al. · Proceedings of the National Academy of Sciences · 2007 · 438 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16