Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

Felix Krueger, Simon Andrews · Bioinformatics · 2011 · 5.6K citations · Full text

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Menno P. Creyghton, Albert W. Cheng, G. Grant Welstead et al. · Proceedings of the National Academy of Sciences · 2010 · 4.4K citations · Full text

Histone Modifications, Epigenetic Change, Genetics +20

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.2K citations · Full text

Transcriptional Regulation, Developmental Biology, Cell Regulation +9

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Marianne Frommer, Louise E. McDonald, David Millar et al. · Proceedings of the National Academy of Sciences · 1992 · 3.2K citations · Full text

Epigenetic Change, Genetics, Dna Methylation +20

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

Xi Chen, Xu Han, Ping Yuan et al. · Cell · 2008 · 2.5K citations

Transcriptional Regulation, Systems Biology, Developmental Biology +14