Facile Removal Strategy forAllyl and Allyloxycarbonyl Protecting Groups Using Solid-SupportedBarbituric Acid under Palladium Catalysis

Abstract

Solid-supported barbituric acid can be used for the palladium(0)-catalyzed deprotection of allyl amines, carbamates, carbonates, esters and ethers. This solid-supported reagent facilitates isolation and purification of the deprotected compounds, especially acids and amines.