Acetaminophen-induced reduction in glutathione-S-transferase A1 in hepatocytes: A role for hepatic nuclear factor 1α and its response element

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Necrostatin‐1 protects against reactive oxygen species (ROS)‐induced hepatotoxicity in acetaminophen‐induced acute liver failure

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Curcumin enhances cell‐surface LDLR level and promotes LDL uptake through downregulation of PCSK9 gene expression in HepG2 cells

Mi‐Hsueh Tai, Po‐Kong Chen, Pei‐Yi Chen et al. · Molecular Nutrition & Food Research · 2014 · 121 citations

Life Sciences, Biochemistry, Molecular Biology +14

Recombinant adenovirus carrying the hepatocyte nuclear factor-1alpha gene inhibits hepatocellular carcinoma xenograft growth in mice

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Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain

Jian Jiang, Jacob J. Briedé, Danyel Jennen et al. · Toxicology Letters · 2015 · 75 citations

Life Sciences, Biochemistry, Pharmacology +17