Nora Zizlsperger

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

Duncan T. Odom, Nora Zizlsperger, D. Benjamin Gordon et al. · Science · 2004 · 1.3K citations · Full text

Genetics, Gene Regulatory Network, Epigenetics +18

Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial

David S. Hong, Michael A. Postow, Bartosz Chmielowski et al. · Clinical Cancer Research · 2023 · 68 citations · Full text

Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity

Uğur Eskiocak, Wilson Guzman, Benjamin Wolf et al. · JCI Insight · 2020 · 45 citations · Full text

Immunology, Immune Regulation, Pathology +21

Eganelisib combined with immune checkpoint inhibitor therapy and chemotherapy in frontline metastatic triple-negative breast cancer triggers macrophage reprogramming, immune activation and extracellular matrix reorganization in the tumor microenvironment

Brenda O’Connell, Charley Hubbard, Nora Zizlsperger et al. · Journal for ImmunoTherapy of Cancer · 2024 · 44 citations · Full text

Abstract P5-16-02: Updated efficacy, safety and translational data from MARIO-3, a phase II open-label study evaluating a novel triplet combination of eganelisib (IPI-549), atezolizumab (atezo), and nab-paclitaxel (nab-pac) as first-line (1L) therapy for locally advanced or metastatic triple-negative breast cancer (TNBC)

Soliman Hatem, Jeffrey B. Hargis, Anthony Elias et al. · Cancer Research · 2022 · 23 citations

Breast Oncology, Oral Eganelisib 30, Immunotherapeutics +20