Tandem eneyne allene-radical cyclization via [2,3] sigmatropic shifts

p-Benzyne. Generation as an intermediate in a thermal isomerization reaction and trapping evidence for the 1,4-benzenediyl structure

Richard R. Jones, Robert G. Bergman · Journal of the American Chemical Society · 1972 · 669 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

Thermal generation of .alpha.,3-dehydrotoluene from (Z)-1,2,4-heptatrien-6-yne

Elaine Y. Kuo, Nathaniel S. Finney · Journal of the American Chemical Society · 1989 · 274 citations

Natural Sciences, Chemistry, Organic Chemistry +5

Biradical formation from acyclic conjugated eneyne-allene system related to neocarzinostatin and esperamicin-calichemicin

Ryu Nagata, Hidenori Yamanaka, Eiichi Okazaki et al. · Tetrahedron Letters · 1989 · 227 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Kinetic evidence for the formation of discrete 1,4-dehydrobenzene intermediates. Trapping by inter- and intramolecular hydrogen atom transfer and observation of high-temperature CIDNP

Thomas P. Lockhart, Paul B. Comita, Robert G. Bergman · Journal of the American Chemical Society · 1981 · 206 citations · Full text

Natural Sciences, Chemistry, Chemical Kinetics +6

DNA-cleavage and antitumor activity of designed molecules with conjugated phosphine oxide-allene-ene-yne functionalities

K.C. Nicolaou, Peter E. Maligres, Jong Heon Shin et al. · Journal of the American Chemical Society · 1990 · 134 citations

Pharmacy, Medicinal Chemistry, Oncology +12