Concepedia

Facile S<sub>N</sub>2‘ Coupling Reactions of Wittig Reagents with Dimethyl Bromomethylfumarate:  Synthesis of Enes, Dienes, and Related Natural Products

Ramesh M. Patel, Narshinha P. Argade

The Journal of Organic Chemistry · 2007 · 16 citations · 17 references

DOI

Concepts

Abstract

A new simple and efficient synthetic protocol with an ample scope has been demonstrated, by employing S(N)2' coupling reactions of a variety of Wittig reagents with dimethyl bromomethylfumarate to obtain the corresponding enes, dienes, and related natural and unnatural products.

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