Concepedia

Synthesis of Silaproline, a New Proline Surrogate

Bertrand Vivet, Florine Cavelier, Jean Martínez

European Journal of Organic Chemistry · 2000 · 73 citations · 21 references

DOI

Concepts

Abstract

The asymmetric synthesis of a new proline surrogate, incorporating the dimethylsilyl group at position 4 of proline using Schöllkopf's bis-lactim ether method, is described.

References

21

Recent developments in the stereoselective synthesis of α-aminoacids

Rudolf O. Duthaler · Tetrahedron · 1994 · 792 citations

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Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis

Torsten Wöhr, Franck Olivier Wahl, Adel Nefzi et al. · Journal of the American Chemical Society · 1996 · 341 citations · Full text

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Enantioselective Syntheses of (<i>R</i>)‐Amino Acids Using <scp>L</scp>‐Valine as Chiral Agent

Ulrich Schöllkopf, Ulrich Groth, Chuanzheng Deng · Angewandte Chemie International Edition in English · 1981 · 255 citations

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Pseudo-Prolines as a Molecular Hinge:  Reversible Induction of<i>cis</i>Amide Bonds into Peptide Backbones

Pascal Dumy, Michael Keller, Declan Ryan et al. · Journal of the American Chemical Society · 1997 · 165 citations

, , +17

Serine derived oxazolidines as secondary structure disrupting, solubilizing building blocks in peptide synthesis

Thomas Haack, Manfred Mutter · Tetrahedron Letters · 1992 · 160 citations

, , +12