Declan Ryan

Phosphotyrosyl Peptides Block Stat3-mediated DNA Binding Activity, Gene Regulation, and Cell Transformation

James Turkson, Declan Ryan, Joon S. Kim et al. · Journal of Biological Chemistry · 2001 · 436 citations · Full text

Pseudo-Prolines as a Molecular Hinge:  Reversible Induction of<i>cis</i>Amide Bonds into Peptide Backbones

Pascal Dumy, Michael Keller, Declan Ryan et al. · Journal of the American Chemical Society · 1997 · 164 citations

Engineering, Reversible Induction, Peptide Engineering +17

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor

Michael P. Winters, Carl Crysler, Nalin L. Subasinghe et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 35 citations · Full text

Medicinal Chemistry, Cxcr2 Receptor, Biochemistry +11

Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)

K.J.M. Moriarty, Hidenori Takahashi, Steven S. Pullen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 32 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +12

Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead

K.J.M. Moriarty, Michael P. Winters, Lei Qiao et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 26 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +12