Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus

Stephen D. Glasgow, Simon Labrecque, Ian V. Beamish, Sarah Aufmkolk, Julien Gibon, Dong Cho Han, Stephanie N. Harris, Paul Dufresne, Paul W. Wiseman, R. Anne McKinney,

Cell Reports · 2018 · 80 citations · 55 references

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Abstract

-dependent recruitment of GluA1-containing AMPARs, promoting the maturation of immature or nascent synapses. These findings identify a central role for activity-dependent release of netrin-1 as a critical effector of synaptic plasticity in the adult hippocampus.

References

55