Publication | Open Access

Targeting dihydrofolate reductase: Design, synthesis and biological evaluation of novel 6-substituted pyrrolo[2,3-d]pyrimidines as nonclassical antifolates and as potential antitumor agents

Medicinal ChemistryBiochemistryMedicineNatural SciencesDihydrofolate ReductaseAnti-cancer AgentPotential Antitumor AgentsDrug DevelopmentPharmacologyDrug DiscoveryNonclassical Antifolates