Electrosynthesis of α-Arylated β-Substituted Cyclopropylphosphonates. Synthesis of a Phosphonic Analogue of Minalcipran

Abstract

[reaction: see text] The synthesis of alpha-arylated beta-substituted cyclopropylphosphonates was efficiently achieved by electroreduction of diethyl alpha,alpha-dichlorobenzylphosphonate in the presence of Michael acceptors in a one-compartment cell equipped with a magnesium sacrificial anode.