Concepedia

New strategy for the regioselective synthesis of 1-phenyl-3-trifluoromethyl-1H-pyrazoles

Nilo Zanatta, Simone S. Amaral, Josiane M. dos Santos, Andreia M. P. W. da Silva, Juliana M. F. M. Schneider, Liana da Silva Fernandes, Hélio G. Bonacorso, Marcos A. P. Martins

Tetrahedron Letters · 2013 · 21 citations · 28 references

DOI

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References

28

Recent advances in the chemistry of α,β-unsaturated trifluoromethylketones

S.V. Druzhinin, Valentine G. Nenajdenko · Tetrahedron · 2007 · 223 citations

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Discovery of 1-[3-(Aminomethyl)phenyl]-<i>N</i>-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1<i>H</i>-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Donald Pinto, Michael J. Orwat, Shuaige Wang et al. · Journal of Medicinal Chemistry · 2001 · 172 citations · Full text

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Synthesis of Monotrifluoromethyl-Substituted Saturated Cycles

Peter Lin, Jinlong Jiang · Tetrahedron · 2000 · 169 citations

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Synthesis of fluorinated heterocycles

Joseph C. Sloop, Carl L. Bumgardner, W. David Loehle · Journal of Fluorine Chemistry · 2002 · 167 citations

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Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors

Sunil Kumar Singh, P. Ganapati Reddy, K. Srinivasa Rao et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 138 citations · Full text

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