Concepedia

Attenuated plasmodium sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice

Dong Zhou, Hong Zheng, Quanxing Liu, Xiao Lu, Deng Xufeng, Jiang Li, Bing Hou, Yong Fu, Feng Zhu, Yan Ding,

Cancer Biology and Medicine · 2019 · 24 citations · 33 references

Open access

Abstract

These findings demonstrate that GAS/MAGE-A3 induces a strong MAGE-A3-specific CD8+ T cell response against lung cancer in vivo, and indicate that GAS is a novel and efficacious antigen delivery vector for antitumor immunotherapy.

References

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Attenuated <i>plasmodium</i> sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice

Abstract

References