Attenuated <i>plasmodium</i> sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice - Concepedia

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Attenuated <i>plasmodium</i> sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice

DOI Full Paper Access

24

Citations

33

References

2019

Year

Dong Zhou, Hong Zheng, Quanxing Liu, Xiao Lu, Deng Xufeng, Jiang Li, Bing Hou, Yong Fu, Feng Zhu, Yan Ding,

Cancer Biology and Medicine

Abstract

These findings demonstrate that GAS/MAGE-A3 induces a strong MAGE-A3-specific CD8<sup>+</sup> T cell response against lung cancer <i>in vivo</i>, and indicate that GAS is a novel and efficacious antigen delivery vector for antitumor immunotherapy.

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