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Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens

Molecular DockingMolecular PharmacologyBiochemistryMedicineRational Drug DesignTyrosine Kinase InhibitorsTethering-fragment-based ScreensPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyMolecular ModelingDrug Discovery