Patrick Cullen

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

D.J. Marcotte, Yuting Liu, Robert M. Arduini et al. · Protein Science · 2010 · 148 citations · Full text

SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage

Mohini Jangi, Christina Fleet, Patrick Cullen et al. · Proceedings of the National Academy of Sciences · 2017 · 125 citations · Full text

<i>Cx3cr1-</i>deficient microglia exhibit a premature aging transcriptome

Stefka Gyoneva, Raghavendra Hosur, David Gosselin et al. · Life Science Alliance · 2019 · 90 citations · Full text

Association between changes in gene signatures expression and disease activity among patients with systemic lupus erythematosus

Michelle Petri, Wei Fu, Ann Ranger et al. · BMC Medical Genomics · 2019 · 82 citations · Full text

Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

Alex R. D. Delbridge, Dann Huh, Margot Brickelmaier et al. · Frontiers in Cellular Neuroscience · 2020 · 66 citations · Full text