Concepedia

Pharmacological Profile of AZD8871 (LAS191351), a Novel Inhaled Dual M3 Receptor Antagonist/β2-Adrenoceptor Agonist Molecule with Long-Lasting Effects and Favorable Safety Profile

Mònica Aparici, Carla Carcasona, Israel Ramos, J.L. Montero, Raquel Otal, J.L. Ortiz, Julio Cortijo, Carlos Puig, Dolors Vilella, Jorge De Alba,

Journal of Pharmacology and Experimental Therapeutics · 2019 · 22 citations · 20 references

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References

20

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD

David A. Lipson, Frank Barnhart, Noushin Brealey et al. · New England Journal of Medicine · 2018 · 1.3K citations · Full text

, , +17

Ba 679 BR, A novel long-acting anticholinergic bronchodilator

Bernd Disse, R Reichl, G. Speck et al. · Life Sciences · 1993 · 163 citations

, , +12

Characterization of Aclidinium Bromide, a Novel Inhaled Muscarinic Antagonist, with Long Duration of Action and a Favorable Pharmacological Profile

Amadeu Gavaldà, Montserrat Miralpeix, Israel Ramos et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 129 citations

, , +17

The Influence of Receptor Kinetics on the Onset and Duration of Action and the Therapeutic Index of NVA237 and Tiotropium

David A. Sykes, Mark R. Dowling, Juliet Leighton-Davies et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 120 citations

, , +17