Concepedia

Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension

Maxime Le Merdy, Jianghong Fan, Michael B. Bolger, Viera Lukáčová, Jessica Spires, Eleftheria Tsakalozou, Vikram Patel, Lin Xu, Sharron Stewart, Ashok Chockalingam,

The AAPS Journal · 2019 · 40 citations · 21 references

References

21

Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes

R. Scott Obach · Drug Metabolism and Disposition · 1999 · 1.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

Shinji Yamashita, Tomoyuki Furubayashi, Makoto Kataoka et al. · European Journal of Pharmaceutical Sciences · 2000 · 565 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Ocular Evaluation of Polyvinyl Alcohol Vehicle in Rabbits

Thomas F. Patton, Joseph R. Robinson · Journal of Pharmaceutical Sciences · 1975 · 202 citations

Medicine, Ophthalmology, Veterinary Ophthalmology +12

Dissolution Modeling: Factors Affecting the Dissolution Rates of Polydisperse Powders

Allan T. K. Lu, Mary E. Frisella, Kevin C. Johnson · Pharmaceutical Research · 1993 · 164 citations

Pharmacy, Chemical Engineering, Pharmaceutical Analysis +15

Mechanistic Studies on Transcorneal Permeation of Pilocarpine

James W. Sieg, Joseph R. Robinson · Journal of Pharmaceutical Sciences · 1976 · 150 citations

Engineering, Pharmacology, Physiology +10