Jianghong Fan

Application of PBPK Modeling and Simulation for Regulatory Decision Making and Its Impact on US Prescribing Information: An Update on the 2018‐2019 Submissions to the US FDA's Office of Clinical Pharmacology

Xinyuan Zhang, Yuching Yang, Manuela Grimstein et al. · The Journal of Clinical Pharmacology · 2020 · 179 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

FDA Approval Summary: Alpelisib Plus Fulvestrant for Patients with HR-positive, HER2-negative, PIK3CA-mutated, Advanced or Metastatic Breast Cancer

Preeti Narayan, Tatiana M. Prowell, Jennifer Gao et al. · Clinical Cancer Research · 2020 · 166 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for <i>in Vivo</i> Dissolution and Absorption of Ionizable Drugs

Bart Hens, Yasuhiro Tsume, Marival Bermejo et al. · Molecular Pharmaceutics · 2017 · 130 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

FDA Approval Summary: Selumetinib for Plexiform Neurofibroma

Denise Casey, Suzanne Demko, A. K. Sinha et al. · Clinical Cancer Research · 2021 · 107 citations

Medicine, Neurology, Pediatrics +12

Up-Regulation of Transporters and Enzymes by the Vitamin D Receptor Ligands, 1α,25-Dihydroxyvitamin D3 and Vitamin D Analogs, in the Caco-2 Cell Monolayer

Jianghong Fan, Shanjun Liu, Yimin Du et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 101 citations

Life Sciences, Molecular Biology, Pharmacology +17