Efficient use of patient-derived organoids as a preclinical model for gynecologic tumors

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

Life Sciences, Cell Biology, Developmental Biology +14

Integrated genomic characterization of endometrial carcinoma

Nature · 2013 · 5.8K citations · Full text

Medicine, Genetics, Oncology +17

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering, Hayley E. Francies, Joshua M. Francis et al. · Cell · 2015 · 2.4K citations · Full text

Medicine, Oncology, Gastrointestinal Oncology +9

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj, Chang‐Il Hwang, Lindsey A. Baker et al. · Cell · 2014 · 2.2K citations · Full text

Medicine, Cell Biology, Oncology +14

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs, Joep de Ligt, Oded Kopper et al. · Cell · 2017 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +12