Concepedia

Dimethyl itaconate protects against lippolysacchride-induced mastitis in mice by activating MAPKs and Nrf2 and inhibiting NF-κB signaling pathways

Caijun Zhao, Peng Jiang, Zhaoqi He, Xin Yuan, Jian Guo, Yanyi Li, Xiaoyu Hu, Yongguo Cao, Yunhe Fu, Naisheng Zhang

Microbial Pathogenesis · 2019 · 59 citations · 19 references

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19

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

Vicky Lampropoulou, Alexey Sergushichev, Monika Bambousková et al. · Cell Metabolism · 2016 · 1.5K citations · Full text

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Bovine Mastitis Pathogens in New York and Pennsylvania: Prevalence and Effects on Somatic Cell Count and Milk Production

David J. Wilson, Rubén N. González, Helena H. Das · Journal of Dairy Science · 1997 · 342 citations · Full text

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Biochemistry of microbial itaconic acid production

Matthias G. Steiger, Marzena L. Blumhoff, Diethard Mattanovich et al. · Frontiers in Microbiology · 2013 · 185 citations · Full text

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Lipoteichoic Acid Induces HO-1 Expression via the TLR2/MyD88/c-Src/NADPH Oxidase Pathway and Nrf2 in Human Tracheal Smooth Muscle Cells

Shyi-Wu Wang, Chiang‐Wen Lee, Chia‐Chi Chang et al. · The Journal of Immunology · 2008 · 149 citations

, , +17