Engineered heart tissue models from hiPSC-derived cardiomyocytes and cardiac ECM for disease modeling and drug testing applications

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell · 2007 · 20.2K citations

Life Sciences, Cell Biology, Developmental Biology +12

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

Harald C. Ott, T Matthiesen, Saik-Kia Goh et al. · Nature Medicine · 2008 · 2.6K citations

Engineering, Bioengineering, Biomedical Engineering +14

Chemically defined generation of human cardiomyocytes

Paul W. Burridge, Elena Matsa, Praveen Shukla et al. · Nature Methods · 2014 · 1.6K citations · Full text

Engineering, Bioengineering, Cell Biology +14

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

Jianhua Zhang, Gisela F. Wilson, Andrew G. Soerens et al. · Circulation Research · 2009 · 1.4K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

Alessandra Moretti, Milena Bellin, Andrea Welling et al. · New England Journal of Medicine · 2010 · 1.2K citations · Full text

Medicine, Cardiology, Genetics +17