Science · 2019 · 742 citations · 48 references
Life SciencesPlant BiologyPlant SciencesMetabolismPlant BiochemistryPlant GenomicsMicrobial Metabolite ProductionPlant MetabolismPlant Natural Product BiosynthesisRoot MicrobiomeRoot-microbe InteractionsSecondary Metabolite BiosynthesisBiosynthetic Pathway AnalysisMetabolic Network AdaptationMetabolic Network ModelsMetabolic Network ReconstructionMicrobiome-associated MetabolitesPlant Metabolite ProfilingRoot-microbiome Interactions
Mix of metabolites tunes root microbiota Uncharacterized biosynthetic genes in plant genomes suggest that plants make a plethora of specialized metabolites. Huang et al. reconstructed three biosynthetic networks from the small mustard plant Arabidopsis thaliana . Promiscuous acyltransferases and dehydrogenases contributed to metabolite diversification. The plant may use these specialized metabolites to modulate the microbiota surrounding its roots. Disruption of the pathways and intervention with purified compounds caused changes in the root microbiota. Science , this issue p. eaau6389
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Cutadapt removes adapter sequences from high-throughput sequencing reads
Marcel Martin · EMBnet journal · 2011 · 35.8K citations · Full text
Search and clustering orders of magnitude faster than BLAST
R. C. Edgar · Bioinformatics · 2010 · 21.7K citations · Full text