Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier

Hirenkumar K. Makadia, Steven J. Siegel

Polymers

Biofunctional MaterialEngineeringNatural PolymerPolymer ScienceBiomaterials Design +10

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

Anders Wittrup, Angela Ai, Xing Liu, +6

Nature Biotechnology

Lipid PreparationProteinlipid InteractionSystems BiologyNatural SciencesLipid-formulated Sirna Release +3

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

James E. Dahlman, Carmen Barnes, Omar F. Khan, +40

Nature Nanotechnology

NanoparticlesNanomedicineCell-based Drug DeliveryEngineeringLow Molecular Weight +5

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

Kim A. Woodrow, Yen Cu, Carmen J. Booth, +3

Nature Materials

Small-interfering RnaIn Vivo Gene TherapyPolymer-drug ConjugateNano-drug DeliveryIntravaginal Gene +6

Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery

Jiangbing Zhou, Jie Liu, Christopher J. Cheng, +5

Nature Materials

EngineeringPolymer ScienceTargeted Gene DeliveryGene DeliveryBiomedical Engineering +1

A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium

Ansgar Santel, Manuela Aleku, Oliver Keil, +10

Gene Therapy

EngineeringRna InterferenceMedicineRna BiologyMouse Vascular Endothelium +9

The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance

Yogesh Patil, Suresh Kumar Swaminathan, Tanmoy Sadhukha, +2

Biomaterials

NanoparticlesNanomedicineNanoparticle-mediated Targeted GeneEngineeringDrug Targeting +8

Therapeutic siRNA: principles, challenges, and strategies.

Kseniya Gavrilov, W. Mark Saltzman

PubMed

EngineeringImmunologyTherapeutic SirnaInnate ImmunityGene Delivery +18

A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes

Stephanie Werth, Beata Urban-Klein, Lige Dai, +5

Journal of Controlled Release

Dna NanotechnologyEngineeringOligonucleotideMolecular BiologyDna Replication +8

Polymeric nanoparticles for siRNA delivery and gene silencing

Yogesh Patil, Jayanth Panyam

International Journal of Pharmaceutics

NanoparticlesNanomedicineEngineeringSirna DeliveryNano-drug Delivery +2