Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

<i>Chlamydomonas IFT</i>88 and Its Mouse Homologue, Polycystic Kidney Disease Gene <i>Tg</i>737, Are Required for Assembly of Cilia and Flagella

Gregory J. Pazour, Bethany L. Dickert, Yvonne Vucica et al. · The Journal of Cell Biology · 2000 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Mutations in DNAH1, which Encodes an Inner Arm Heavy Chain Dynein, Lead to Male Infertility from Multiple Morphological Abnormalities of the Sperm Flagella

Mariem Ben Khelifa, Charles Coutton, Raoudha Zouari et al. · The American Journal of Human Genetics · 2013 · 479 citations · Full text

Medicine, Genetics, Molecular Genetics +16

Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles

James A. Deane, Douglas G. Cole, E. Scott Seeley et al. · Current Biology · 2001 · 391 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

Erica E. Davis, Qi Zhang, Qin Liu et al. · Nature Genetics · 2011 · 379 citations · Full text

Life Sciences, Genetics, Molecular Genetics +5