The novel immunosuppressant prenylated quinolinecarboxylic acid-18 (PQA-18) suppresses macrophage differentiation and cytotoxicity in xenotransplantation

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

Dong Niu, Hong‐Jiang Wei, Lin Lin et al. · Science · 2017 · 752 citations

Life Sciences, Biotechnology, Molecular Medicine +17

Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

Paul S. Changelian, Mark E. Flanagan, Douglas J. Ball et al. · Science · 2003 · 670 citations · Full text

Medicine, Immunology, Pharmacology +17

Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

Kamran Ghoreschi, Michael I. Jesson, Li Xiong et al. · The Journal of Immunology · 2011 · 644 citations · Full text

Life Sciences, Immunology, Pharmacology +17

The JAK inhibitor, tofacitinib, reduces the T cell stimulatory capacity of human monocyte-derived dendritic cells

Satoshi Kubo, Kunihiro Yamaoka, Masahiro Kondo et al. · Annals of the Rheumatic Diseases · 2013 · 171 citations

Life Sciences, Immunology, Pharmacology +17

Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation

Anne Lehtonen, Sampsa Matikainen, Minja Miettinen et al. · Journal of Leukocyte Biology · 2002 · 152 citations

Life Sciences, Immunology, Molecular Biology +15