Concepedia

Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation

Taeseung Lee, Subin Yun, Ji Hoon Jeong, Tae Woo Jung

Molecular and Cellular Endocrinology · 2019 · 188 citations · 32 references

DOI

Concepts

References

32

TLR4 links innate immunity and fatty acid–induced insulin resistance

Hang Shi, Maia V. Kokoeva, Karen Inouye et al. · Journal of Clinical Investigation · 2006 · 3.6K citations · Full text

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A central role for JNK in obesity and insulin resistance

Jiro Hirosumi, Gürol Tuncman, Lufen Chang et al. · Nature · 2002 · 3.3K citations

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Interleukin-1–Receptor Antagonist in Type 2 Diabetes Mellitus

Claus M. Larsen, Mirjam Faulenbach, Allan Vaag et al. · New England Journal of Medicine · 2007 · 1.8K citations · Full text

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Selective interaction of JNK protein kinase isoforms with transcription factors.

Shreyasi Gupta, Tyler W. Barrett, Alan J. Whitmarsh et al. · The EMBO Journal · 1996 · 1.3K citations · Full text

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Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance

Daniela Miti Lemos Tsukumo, Carvalho Filho, José Barreto Campello Carvalheira et al. · Diabetes · 2007 · 817 citations · Full text

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