Bortezomib improved the joint manifestations of rheumatoid arthritis in three patients

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

Kirsten Neubert, Silke Meister, Katrin Moser et al. · Nature Medicine · 2008 · 576 citations

Medicine, Immunology, Pharmacology +16

Activation of the transcription factor nuclear factor‐κB in human inflamed synovial tissue

R. Marok, Paul G. Winyard, A Coumbe et al. · Arthritis & Rheumatism · 1996 · 317 citations

Medicine, Immunology, Pathology +10

Role of the proteasome and NF-κB in streptococcal cell wall-induced polyarthritis

Vito J. Palombella, Elaine M. Conner, John W. Fuseler et al. · Proceedings of the National Academy of Sciences · 1998 · 286 citations

Life Sciences, Immunology, Molecular Biology +17

Bortezomib attenuates murine collagen-induced arthritis

Annals of the Rheumatic Diseases · 2008 · 81 citations · Full text

Medicine, Immunology, Pathobiology +17

Attenuation of pain and inflammation in adjuvant‐induced arthritis by the proteasome inhibitor MG132

Aisha Ahmed, Jian Li, Mahmood Ahmed et al. · Arthritis & Rheumatism · 2010 · 67 citations

Medicine, Immunology, Pharmacology +17