Suppressing UPR-dependent overactivation of FGFR3 signaling ameliorates SLC26A2-deficient chondrodysplasias

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Developmental Biology, Vertebrate Skeletogenesis, Bone Morphogenic Protein +7

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

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Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

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A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

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Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway

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Regenerative Medicine, Mechanobiology, Molecular Physiology +9