Concepedia

Total Synthesis of (−)‐Amphidinolide K

Haye Min Ko, Chung Whan Lee, Hyung Kyoo Kwon, Heaseung Sophia Chung, Soo Young Choi, Young Keun Chung, Eun Lee

Angewandte Chemie International Edition · 2009 · 57 citations · 17 references

DOI

Concepts

Abstract

Macrolide magic: An enyne cross-metathesis reaction of an alkynyl boronate with an alkene derivative as well as a radical cyclization reaction of a homopropargylic beta-alkoxyacrylate are the key transformations in the total synthesis of the cytotoxic macrolide (-)-amphidinolide K.

References

17

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Total synthesis of the macrolide antibiotic rutamycin B

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Total Synthesis of (+)-Amphidinolide K

David R. Williams, Kevin G. Meyer · Journal of the American Chemical Society · 2001 · 128 citations

, , +8

Use of Thallium(I) Ethoxide in Suzuki Cross Coupling Reactions

Scott A. Frank, Hou Chen, Roxanne K. Kunz et al. · Organic Letters · 2000 · 127 citations

, , +10