Dual inhibition of Akt and ERK signaling induces cell senescence in triple-negative breast cancer

Cancer statistics, 2018

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2018 · 16.8K citations · Full text

Comprehensive molecular portraits of human breast tumours

Nature · 2012 · 12.1K citations · Full text

Breast Oncology, Comprehensive Molecular Portraits, Tumor Heterogeneity +6

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

Todd Waldman, K. W. Kinzler, Bert Vogelstein · PubMed · 1995 · 1.2K citations

Cell Death, Pathology, P53-dependent G1 Arrest +16

PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

Violeta Serra, Maurizio Scaltriti, Ludmila Prudkin et al. · Oncogene · 2011 · 530 citations · Full text

Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.

Shotaro Naito, Andrew C. von Eschenbach, Raffaella Giavazzi et al. · PubMed · 1986 · 526 citations

Urology, Surgical Oncology, Nude Mice +15