Concepedia

Publication | Open Access

LMO7 Is a Negative Feedback Regulator of Transforming Growth Factor β Signaling and Fibrosis

DOIFull Paper Access

81

Citations

37

References

2019

Year

Yi Xie, Allison C. Ostriker, Jin Yu, Haidi Hu, Ashley Sizer, Gang Peng, Aaron H. Morris, Changwan Ryu, Erica L. Herzog, Themis R. Kyriakides,
Circulation

Abstract

LMO7 is induced by TGF-β and serves to limit vascular fibrotic responses through negative feedback regulation of the TGF-β pathway. This mechanism has important implications for intimal hyperplasia, wound healing, and fibrotic diseases.

References

YearCitations

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