Nature Immunology · 2019 · 133 citations · 35 references
Life SciencesCell BiologyMolecular BiologyCell SignalingInflammationSignal TransductionCaspase ActivationImmune Checkpoint RegulationImmune CheckpointsInflammasome ActivationInflammatory Cell SignalingInflammatory SignalingCaspase-mediated Inflammatory SignalingInnate Immune Checkpoint Regulation
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
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Cryopyrin activates the inflammasome in response to toxins and ATP
Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi et al. · Nature · 2011 · 2.5K citations
Inflammatory caspases are innate immune receptors for intracellular LPS
Jianjin Shi, Yue Zhao, Yupeng Wang et al. · Nature · 2014 · 2.2K citations