Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios, +3

Nature Cell Biology

Novel MechanismSystems BiologyNatural SciencesExosome-mediated TransferExtracellular Microvesicles +8

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin, +3

Nature Biotechnology

Cell-based Drug DeliveryNanomedicineSystemic InjectionMedicineTargeted Drug Delivery +7

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

Eva van Rooij, Lillian B. Sutherland, Jeffrey E. Thatcher, +5

Proceedings of the National Academy of Sciences

Heart FailureImmunologyPathologySpecific MicrornasAcute Myocardial Infarction +14

Kruppel-Like Factor 15 Modulates Renal Interstitial Fibrosis by ERK/MAPK and JNK/MAPK Pathways Regulation

Xiang Gao, Guiqun Wu, Xiangchen Gu, +2

Kidney & Blood Pressure Research

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

Margaret Alexander, Ruozhen Hu, Marah C. Runtsch, +7

Nature Communications

Biodistribution and delivery efficiency of unmodified tumor-derived exosomes

Tyson Smyth, Max Kullberg, Noeen Malik, +3

Journal of Controlled Release

Cell-based Drug DeliveryNanomedicineEngineeringTargeted Drug DeliveryExtracellular Microvesicles +4

TGF-β/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

Wei Qin, Arthur C.K. Chung, Xiao Ru Huang, +5

Journal of the American Society of Nephrology

Translational MedicineUrologyFibrosisMicrorna MicroarrayTherapeutic Microrna +13

Chronic Kidney Disease Progression

Allison A. Eddy, Eric G. Neilson

Journal of the American Society of Nephrology

Glomerular DiseaseGlomerulonephritisHemodialysisUrologyRenal Disease +9

TGF-β isoforms in renal fibrogenesis

Ling Yu, Wayne A. Border, Yufeng Huang, +1

Kidney International

FibrosisDevelopmental BiologyUrologyRenal PathologyTgf-β Isoforms +7

miRNA‐23a/27a attenuates muscle atrophy and renal fibrosis through muscle‐kidney crosstalk

Aiqing Zhang, Min Li, Bin Wang, +3

Journal of Cachexia Sarcopenia and Muscle