Concepedia

CD70 defines a subset of proinflammatory and CNS-pathogenic TH1/TH17 lymphocytes and is overexpressed in multiple sclerosis

Tessa Dhaeze, Laurence Tremblay, Catherine Lachance, Evelyn Peelen, Stéphanie Zandee, Camille Grasmuck, Lyne Bourbonnière, Sandra Larouche, Xavier Ayrignac, Rose‐Marie Rébillard,

Cellular and Molecular Immunology · 2019 · 67 citations · 48 references

DOIFull text

Open access

Concepts

References

48

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

Chris H. Polman, Stephen C. Reingold, Brenda Banwell et al. · Annals of Neurology · 2011 · 9.8K citations · Full text

, , +10

IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells

Thomas Korn, Estelle Bettelli, Wenda Gao et al. · Nature · 2007 · 1.8K citations

, , +14

Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

Eva V. Acosta Rodríguez, Laura Rivino, Jens Geginat et al. · Nature Immunology · 2007 · 1.8K citations

, , +16

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

Hania Kébir, Katharina Kreymborg, Igal Ifergan et al. · Nature Medicine · 2007 · 1.7K citations · Full text

, , +16

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

Laura Codarri Deak, Gábor Gyülvészi, Vinko Toševski et al. · Nature Immunology · 2011 · 1.2K citations

, , +17