Fast gapped-read alignment with Bowtie 2

Ben Langmead, Steven L. Salzberg

Nature Methods

Long-read SequencingSequence AssemblyNatural SciencesComputational BiologyMolecular Biology +5

BEDTools: a flexible suite of utilities for comparing genomic features

Aaron R. Quinlan, Ira M. Hall

Bioinformatics

An integrated encyclopedia of DNA elements in the human genome

Nature

ChromatinDna SequencingDnaNatural SciencesGenetics +10

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox, +8

Science

Single Crispr ArrayEngineeringShort RnasGeneticsSynthetic Biology +10

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert, +2

Nature Biotechnology

EngineeringGeneticsMultiomicsSingle-cell Transcriptomic DataTranscriptomics Technology +15

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright, +3

Nature Protocols

EngineeringGenome SurgeryGeneticsSynthetic BiologyGenetic Engineering +5

Near-optimal probabilistic RNA-seq quantification

Nicolas Bray, Harold Pimentel, Páll Melsted, +1

Nature Biotechnology

Functional GenomicsEngineeringGeneticsRna Structure PredictionComputational Biology +5

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Suhas S.P. Rao, Miriam Huntley, Neva C. Durand, +8

Cell

ChromatinFunctional GenomicsChromatin StructureChromatin RemodelingNatural Sciences +12

Detection of nonneutral substitution rates on mammalian phylogenies

Katherine S. Pollard, Melissa J. Hubisz, Kate R. Rosenbloom, +1

Genome Research

GeneticsGenomicsPhylogeneticsMolecular EcologyMolecular Adaptation +14

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

Jacqueline A. L. MacArthur, Emily Bowler-Barnett, María Cerezo, +14

Nucleic Acids Research

GeneticsGenetic EpidemiologyGenomicsBioinformatics DatabaseGenome-wide Association Studies +21