Tumor necrosis factor-α regulates angiogenesis of BeWo cells via synergy of PlGF/VEGFR1 and VEGF-A/VEGFR2 axes

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +15

Vascular endothelial growth factor (VEGF) and its receptors

Gera Neufeld, Tzafra Cohen, Stela Gengrinovitch et al. · The FASEB Journal · 1999 · 3.5K citations

Medicine, Cell Biology, Oncology +17

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Florian R. Greten, Lars Eckmann, Tim F. Greten et al. · Cell · 2004 · 2.4K citations · Full text

Medicine, Immunology, Oncology +16

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

Peter Carmeliet, Lieve Moons, Aernout Luttun et al. · Nature Medicine · 2001 · 1.7K citations

Medicine, Pathobiology, Tumor Microenvironment +13

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

Barry J. Sugarman, Bharat B. Aggarwal, Philip E. Hass et al. · Science · 1985 · 1.6K citations

Medicine, Cancer Biology, Oncology +8