SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance - Concepedia

Concepedia

Publication | Open Access

SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance

DOI Full Paper Access

95

Citations

21

References

2018

Year

Isaac Wasserman, Lik Hang Lee, Shuji Ogino, Michael R. Marco, Chao Wu, Xi Chen, Jashodeep Datta, Eran Sadot, Bryan Szeglin, José G. Guillem,

Clinical Cancer Research

Abstract

Our data show SMAD4 loss correlates with worse clinical outcome, resistance to chemotherapy, and decreased immune infiltrate, supporting its use as a prognostic marker in patients with colorectal cancer.

References

	Year	Citations

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