Cancer-associated fibroblasts promote the stemness of CD24+ liver cells via paracrine signaling

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Louis Vermeulen, Felipe de Sousa e Melo, Maartje van der Heijden et al. · Nature Cell Biology · 2010 · 1.8K citations

Life Sciences, Cancer Biology, Cell Biology +10

CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

Shicheng Su, Jianing Chen, Herui Yao et al. · Cell · 2018 · 1.3K citations · Full text

Medicine, Cancer Biology, Oncology +12

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

Christina Scheel, Elinor Ng Eaton, Hsin‐Jung Li et al. · Cell · 2011 · 856 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Double‐blind randomized controlled clinical trial of the interleukin‐6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate

Ravinder N. Maini, Peter C. Taylor, Jacek Szechiński et al. · Arthritis & Rheumatism · 2006 · 792 citations

Medicine, Pharmacology, Pharmacotherapy +17

Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

Shanshan Wan, Ende Zhao, Ilona Kryczek et al. · Gastroenterology · 2014 · 679 citations · Full text

Life Sciences, Cancer Biology, Oncology +14