IL-17A contributes to myocardial ischemic injury by activating NLRP3 inflammasome in macrophages through AMPKα/p38MAPK/ERK1/2 signal pathway in mice

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

Masanori Kawaguchi, Masafumi Takahashi, Takeki Hata et al. · Circulation · 2011 · 862 citations

Veterinary Medicine, Cardiology, Pathobiology +17

Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

Duygu Sağ, David Carling, Robert D. Stout et al. · The Journal of Immunology · 2008 · 796 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

Eleonora Mezzaroma, Stefano Toldo, Daniela Farkas et al. · Proceedings of the National Academy of Sciences · 2011 · 621 citations

Life Sciences, Cardiology, Pharmacology +16

Macrophage Depletion Impairs Wound Healing and Increases Left Ventricular Remodeling after Myocardial Injury in Mice

Machteld J. van Amerongen, Martin C. Harmsen, Nico van Rooijen et al. · American Journal Of Pathology · 2007 · 542 citations · Full text

Medicine, Cardiology, Immunology +16

The Th17/Treg imbalance in patients with acute coronary syndrome

Xiang Cheng, Yingjun Ding, Qingqing Fu et al. · Clinical Immunology · 2008 · 487 citations

Medicine, Cardiology, Internal Medicine +13