Parecoxib, a selective blocker of cyclooxygenase-2, directly inhibits neuronal delayed-rectifier K+ current, M-type K+ current and Na+ current

Modulation of K+ current by frequency and external [K+]: A tale of two inactivation mechanisms

Thomas Baukrowitz, Gary Yellen · Neuron · 1995 · 382 citations · Full text

Electrical Engineering, Hyperpolarization (Biology), Physiology +3

Selective control of cortical axonal spikes by a slowly inactivating K⁺current

Yousheng Shu, Yuguo Yu, Jing Yang et al. · Proceedings of the National Academy of Sciences · 2007 · 214 citations · Full text

<i>N</i>-[[(5-Methyl-3-phenylisoxazol-4-yl)- phenyl]sulfonyl]propanamide, Sodium Salt, Parecoxib Sodium:  A Potent and Selective Inhibitor of COX-2 for Parenteral Administration

John J. Talley, Stephen R. Bertenshaw, David Brown et al. · Journal of Medicinal Chemistry · 2000 · 211 citations · Full text

Pharmaceutical Science, Altmetric Attention Score, Pharmacotherapy +19

The COX-2 inhibitor parecoxib is neuroprotective but not antiepileptogenic in the pilocarpine model of temporal lobe epilepsy

N. Polascheck, Marion Bankstahl, Wolfgang Löscher · Experimental Neurology · 2010 · 157 citations

Neurophysiology, Neuroanatomy, Medicine +13

Two Types of K⁺Channel Subunit, Erg1 and KCNQ2/3, Contribute to the M-Like Current in a Mammalian Neuronal Cell

A. A. Selyanko, J. K. Hadley, Ian Wood et al. · Journal of Neuroscience · 1999 · 132 citations · Full text

Synaptic Transmission, Neurotransmission, Cellular Neurobiology +21