Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

Mary P. Hall, James Unch, Brock F. Binkowski et al. · ACS Chemical Biology · 2012 · 1.6K citations · Full text

Engineering, Bioluminescence Methodologies, Molecular Biology +25

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

John R. Teerlink, Gad Cotter, Beth A. Davison et al. · The Lancet · 2012 · 896 citations

Heart Failure, Cardiac Anaesthesia, Cardiogenic Shock +10

Activation of Orphan Receptors by the Hormone Relaxin

Sheau Yu Hsu, Koji Nakabayashi, Shinya Nishi et al. · Science · 2002 · 783 citations

NanoBRET—A Novel BRET Platform for the Analysis of Protein–Protein Interactions

Thomas Machleidt, Carolyn C. Woodroofe, Marie K. Schwinn et al. · ACS Chemical Biology · 2015 · 477 citations · Full text

Protein–protein Interactions, Engineering, Protein Assembly +18

Application of BRET to monitor ligand binding to GPCRs

Leigh A. Stoddart, Elizabeth K. M. Johnstone, Amanda J. Wheal et al. · Nature Methods · 2015 · 255 citations · Full text

Molecular Recognition, Biochemistry, Natural Sciences +3