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Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry

Justine Badée, NaHong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt, Stephen Fowler

Drug Metabolism and Disposition · 2018 · 32 citations · 41 references

Open access

References

41

EVALUATION OF 3′-AZIDO-3′-DEOXYTHYMIDINE, MORPHINE, AND CODEINE AS PROBE SUBSTRATES FOR UDP-GLUCURONOSYLTRANSFERASE 2B7 (UGT2B7) IN HUMAN LIVER MICROSOMES: SPECIFICITY AND INFLUENCE OF THE UGT2B7*2 POLYMORPHISM

Michael H. Court, Soundarajan Krishnaswamy, Qin Hao et al. · Drug Metabolism and Disposition · 2003 · 247 citations

SELECTIVITY OF SUBSTRATE (TRIFLUOPERAZINE) AND INHIBITOR (AMITRIPTYLINE, ANDROSTERONE, CANRENOIC ACID, HECOGENIN, PHENYLBUTAZONE, QUINIDINE, QUININE, AND SULFINPYRAZONE) “PROBES” FOR HUMAN UDP-GLUCURONOSYLTRANSFERASES

Verawan Uchaipichat, Peter I. Mackenzie, David J. Elliot et al. · Drug Metabolism and Disposition · 2005 · 244 citations

Specificity and Regioselectivity of the Conjugation of Estradiol, Estrone, and Their Catecholestrogen and Methoxyestrogen Metabolites by Human Uridine Diphospho-glucuronosyltransferases Expressed in Endometrium

Johanie Lépine, Olivier Bernard, Marie Plante et al. · The Journal of Clinical Endocrinology & Metabolism · 2004 · 202 citations · Full text

Characterization of Raloxifene Glucuronidation in Vitro: Contribution of Intestinal Metabolism to Presystemic Clearance

Daniel C. Kemp, Peter W. Fan, Jeffrey Stevens · Drug Metabolism and Disposition · 2002 · 191 citations

The “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities

Andrew Rowland, Kathleen Knights, Peter I. Mackenzie et al. · Drug Metabolism and Disposition · 2008 · 180 citations