International Journal of Molecular Biology Open Access · 2018 · 13 citations · 10 references
Life SciencesBiochemistryMolecular BiologyEnzymologyProtein FoldingStructural BiologyGlobular ProteinsProtein ConformationProtein DomainsProtein Folding ThermodynamicsProtein StructureStructural DomainsFoldability CriteriaProtein Folding AnalysisProtein Folding DomainsProtein Folding PropensityProtein Folding StabilityProtein FoldsThermodynamic Stability Determinants
In recent time, I have reported that the existence of carbon value in carbon domain is determining to be the factor of all stable regions in a given protein here. Again conclude that the Globular Amphipathic Domain (GAD) based on carbon value is observed to be the fact of maintenance and responsible for stability of the protein and activity. CARd program explains all this phenomenon of protein to fold. Average value of all possible outerlengths is looked out here. Analysis of some enzyme proteins, including super oxide dismutase and ribulose-phosphate 3-epimerase are looked in details here up again. Normally a protein folds because of this GAD. Observed that GAD dominates of all forces of interactions that has been discussed so far. Hope to find solution for folding of protein to occur all time.
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