Association of long-term PM2.5 exposure with traditional and novel lipid measures related to cardiovascular disease risk

Laura A. McGuinn, Alexandra Schneider, Robert W. McGarrah, Cavin Ward‐Caviness, Lucas Neas, Qian Di, Joel Schwartz, Elizabeth R. Hauser, William E. Kraus, Wayne E. Cascio,

Environment International · 2018 · 145 citations · 23 references

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Abstract

BACKGROUND: exposure and traditional and novel lipoprotein measures in a cardiac catheterization cohort in North Carolina. METHODS: . Models were adjusted for age, sex, race/ethnicity, history of smoking, area-level education, urban/rural status, body mass index, and diabetes. RESULTS: exposure, we observed increases in total and small LDL-P, LDL-C, TRL-P, apoB, total cholesterol, and triglycerides. The percent change from the mean outcome level was 2.00% (95% CI: 1.38%, 2.64%) for total LDL-P and 2.25% (95% CI: 1.43%, 3.06%) for small LDL-P. CONCLUSION: exposure was associated with increases in several lipoprotein concentrations. This abstract does not necessarily reflect U.S. EPA policy.

References

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