Concepedia

Butyrate Modulates Inflammation in Chondrocytes via GPR43 Receptor

Claudio Pirozzi, Vera Francisco, Francesca Guida, Rodolfo Gómez, Francisca Lago, Jesús Pino, Rosaria Meli, Oreste Gualillo

Cellular Physiology and Biochemistry · 2018 · 94 citations · 28 references

DOIFull text

Open access

Abstract

Taken together, our data suggest the potential application of sodium butyrate as a novel candidate in a multi-target approach for the treatment of chondrocyte inflammation and cartilage degenerative process.

References

28

Butyrate Inhibits NF-κB Activation in Lamina Propria Macrophages of Patients with Ulcerative Colitis

H Lührs, Tobias Gerke, Justus Müller et al. · Scandinavian Journal of Gastroenterology · 2002 · 460 citations

Butyrate Regulates Liver Mitochondrial Function, Efficiency, and Dynamics in Insulin-Resistant Obese Mice

Maria Pina Mollica, Giuseppina Mattace Raso, Gina Cavaliere et al. · Diabetes · 2017 · 342 citations

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SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor

Marco Aurélio Ramirez Vinolo, Gail Ferguson, Suhasini Kulkarni et al. · PLoS ONE · 2011 · 282 citations · Full text

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kB, MAPkinase and p53 pathways

Victoria Grandage, Rosemary E. Gale, David C. Linch et al. · Leukemia · 2005 · 280 citations

, , +10

Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet

Giuseppina Mattace Raso, Raffaele Simeoli, Roberto Russo et al. · PLoS ONE · 2013 · 198 citations · Full text