Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6K citations · Full text

Histone Modifications, Chromatin, Dna Methyltransferases Dnmt3a +13

Induction of Tumors in Mice by Genomic Hypomethylation

François Gaudet, John Hodgson, Amir Eden et al. · Science · 2003 · 1.5K citations

Tumor Biology, Genome Instability, Chromatin +14

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

Amir Eden, François Gaudet, Alpana Waghmare et al. · Science · 2003 · 1.4K citations

Epigenetic Change, Genetics, Dna Methylation +16

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

Masahiro Kaneda, Masaki Okano, Kenichiro Hata et al. · Nature · 2004 · 1.4K citations

Chromatin, Developmental Biology, Essential Role +13

The Risk of Major Birth Defects after Intracytoplasmic Sperm Injection and in Vitro Fertilization

Michèle Hansen, Jennifer J. Kurinczuk, Carol Bower et al. · New England Journal of Medicine · 2002 · 1.1K citations · Full text