Concepedia

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy

Jasper Fuk‐Woo Chan, Zheng Zhu, Hin Chu, Shuofeng Yuan, Kenn Ka‐Heng Chik, Chris Chung‐Sing Chan, Vincent Kwok‐Man Poon, Cyril Chik‐Yan Yip, Xi Zhang, Jessica Oi‐Ling Tsang,

Antiviral Research · 2018 · 46 citations · 40 references

References

40

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

Mark R. Duffy, Tai-Ho Chen, W. Thane Hancock et al. · New England Journal of Medicine · 2009 · 3.2K citations · Full text

Veterinary Medicine, Infectious Diseases, Internal Medicine +17

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

Craig W. Lindsley, Zhijian Zhao, William Leister et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 501 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

Hin Chu, Jie Zhou, Bosco Ho‐Yin Wong et al. · The Journal of Infectious Diseases · 2015 · 472 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus

Jasper Fuk‐Woo Chan, Kwok‐Hung Chan, Richard Yi Tsun Kao et al. · Journal of Infection · 2013 · 390 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacotherapy +14

A Susceptible Mouse Model for Zika Virus Infection

Stuart Dowall, Victoria Graham, Emma Rayner et al. · PLoS neglected tropical diseases · 2016 · 313 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17