Concepedia

Enzymatic synthesis of sitagliptin intermediate using a novel ω-transaminase

Geon‐Hee Kim, Hyunwoo Jeon, Taresh P. Khobragade, Mahesh D. Patil, Sihyong Sung, Sanghan Yoon, Yumi Won, In Suk Choi, Hyungdon Yun

Enzyme and Microbial Technology · 2018 · 39 citations · 51 references

DOI

Concepts

References

51

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff et al. · Science · 2010 · 1.7K citations

, , +16

Transaminase biocatalysis: optimization and application

Fei Guo, Per Berglund · Green Chemistry · 2016 · 469 citations · Full text

, , +17

Rational assignment of key motifs for function guides in silico enzyme identification

Matthias Höhne, Sebastian Schätzle, Helge Jochens et al. · Nature Chemical Biology · 2010 · 369 citations

, , +17

Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

Iustina Slabu, James L. Galman, Richard C. Lloyd et al. · ACS Catalysis · 2017 · 366 citations · Full text

, , +17

Jasplakinolide, a cyclodepsipeptide from the marine sponge, SP.

Phillip Crews, L. Manes, Mark A. Boehler · Tetrahedron Letters · 1986 · 317 citations

, , +6