Biocatalytic Routes to Optically Active Amines

Matthias Höhne, Uwe T. Bornscheuer

ChemCatChem

Optically Active AminesAmino AcidsBiochemistryPhotochemistryNatural Sciences +10

Rational assignment of key motifs for function guides in silico enzyme identification

Matthias Höhne, Sebastian Schätzle, Helge Jochens, +2

Nature Chemical Biology

Sequence MotifKey MotifsFunctional GenomicsBiochemistrySilico Enzyme Identification +12

Efficient Asymmetric Synthesis of Chiral Amines by Combining Transaminase and Pyruvate Decarboxylase

Matthias Höhne, Steffen Kühl, Karen Robins, +1

ChemBioChem

Chiral AminesEngineeringBiochemistryAmino AcidNatural Sciences +13

Rapid and Sensitive Kinetic Assay for Characterization of ω-Transaminases

Sebastian Schätzle, Matthias Höhne, Erik Redestad, +2

Analytical Chemistry

EngineeringEnzymatic ModificationBiosynthesisBioanalysisBiochemical Engineering +15

Asymmetric Reductive Amination of Ketones Catalyzed by Imine Reductases

Dennis Wetzl, Martin Gand, Alfred Ross, +7

ChemCatChem

Imine ReductasesEngineeringBiochemistryNatural SciencesBiocatalysis +10

Enzymatic Asymmetric Synthesis of Enantiomerically Pure Aliphatic, Aromatic and Arylaliphatic Amines with (<i>R</i>)‐Selective Amine Transaminases

Sebastian Schätzle, Fabian Steffen‐Munsberg, Ahmad Thontowi, +3

Advanced Synthesis & Catalysis

EngineeringAmine TransaminasesEnantiomerically Pure AliphaticEscherichia ColiOrganic Chemistry +16

One-step asymmetric synthesis of (R)- and (S)-rasagiline by reductive amination applying imine reductases

Philipp Matzel, Martin Gand, Matthias Höhne

Green Chemistry

Imine ReductasesEngineeringBiochemistryReductive AminationOrganic Chemistry +9

Engineering the Active Site of the Amine Transaminase from <i>Vibrio fluvialis</i> for the Asymmetric Synthesis of Aryl–Alkyl Amines and Amino Alcohols

Alberto Nobili, Fabian Steffen‐Munsberg, Hannes Kohls, +4

ChemCatChem

Amine TransaminaseBulky KetonesEngineeringOrganic ChemistryEnzymatic Modification +15

Revealing the Structural Basis of Promiscuous Amine Transaminase Activity

Fabian Steffen‐Munsberg, Clare Vickers, Ahmad Thontowi, +7

ChemCatChem

Protein ChemistryBiochemistryNatural SciencesEnzyme CatalysisProtein Biosynthesis +11

Combining Photo‐Organo Redox‐ and Enzyme Catalysis Facilitates Asymmetric C‐H Bond Functionalization

Wuyuan Zhang, Elena Fernández‐Fueyo, Frank Hollmann, +5

European Journal of Organic Chemistry